At the heart of Anthropic’s rapid rise is a sibling team whose approach to artificial intelligence stands in stark contrast to the industry’s typical fast-paced, attention-driven model. Daniela Amodei, co-founder and head of safety and research at Anthropic, exudes a calm, grounded presence that belies her role in one of the most influential AI companies in the world. Her demeanor — warm, thoughtful, and refreshingly human — sets her apart from the high-profile, often flamboyant figures dominating the AI space. Five years ago, Daniela and her brother Dario, who serves as Anthropic’s CEO, left OpenAI with a small group of top researchers. Their departure wasn’t a retreat, as some might assume, but a deliberate pivot. They were running toward a vision: that AI could be both safe and commercially successful, and that long-term value would come not from viral consumer apps, but from building reliable, trustworthy systems for businesses. While OpenAI launched ChatGPT in late 2022, sparking a global AI frenzy, Anthropic took a different path. It moved slowly, prioritizing safety, transparency, and robustness over speed and spectacle. The result? A model, Claude, that has become a preferred tool for enterprises that demand accuracy, security, and compliance. Daniela, who has a background in cognitive science and machine learning, is the quiet force behind the company’s ethical and technical foundation. Where her brother speaks in long-term visions of superintelligence, she focuses on the details that make AI systems trustworthy — the kind of work that doesn’t make headlines but is essential to real-world adoption. Her story is emblematic of Anthropic’s strategy. The company has grown its business customer base from under 1,000 to more than 300,000 in just two years. Nearly 80% of Claude’s usage now comes from outside the U.S., and its client list includes major global players like Novo Nordisk, the Norwegian sovereign wealth fund, Bridgewater, Stripe, and Slack. These are not casual users — they are organizations that depend on AI to power critical operations. Analysts like Gil Luria of D.A. Davidson point to a key shift in the AI market: the frontier is no longer about making chatbots more conversational, but about solving real, high-stakes problems in coding, science, and business. Claude has excelled in these areas, particularly among developers, where it has earned a reputation as a top-tier coding assistant. Sameer Dholakia, a partner at Bessemer Ventures, one of Anthropic’s early investors, said the company’s focus on trust and safety was a major differentiator. “Enterprise buyers don’t churn. They need reliability. And that’s exactly what Anthropic built.” While OpenAI still leads in user numbers — with ChatGPT reaching nearly 900 million weekly active users — Anthropic is closing the gap, especially in the B2B space. Today, about 85% of Anthropic’s revenue comes from business customers, compared to over 60% for OpenAI, which remains more consumer-focused. Daniela Amodei remains grounded in this success. “We’re not here to chase attention,” she said. “We’re here to do the work.” That work — the careful, deliberate, and human-centered development of AI — may be the key to the next phase of the industry’s evolution.