NVIDIA has joined the U.S. Department of Energy’s (DOE) Genesis Mission as a private industry partner, marking a major step in strengthening American leadership in artificial intelligence. The initiative, established under a recent executive order by President Trump, aims to reinforce U.S. dominance in AI across three critical domains: energy, scientific research, and national security. As part of the partnership, NVIDIA will help develop a unified discovery platform that connects government, industry, and academic institutions to accelerate innovation. The Genesis Mission is expected to double the productivity and impact of American science and engineering, driving breakthroughs in energy independence, scientific discovery, and national defense. NVIDIA’s role will center on integrating its advanced AI, high-performance computing, and accelerated computing technologies into the DOE’s mission-critical projects. In a key development, NVIDIA and the DOE have signed a memorandum of understanding (MOU) outlining the scope of their collaboration. The agreement covers a broad range of strategic priorities, including AI for manufacturing and supply chain optimization, open-source AI development, fission and fusion energy, robotics, AI-powered digital twins, quantum computing, and scientific applications that leverage AI for real-time decision-making at the edge. These efforts focus on using AI to design, operate, and control complex systems—such as nuclear reactors, experimental facilities, infrastructure simulations, and autonomous laboratories. The collaboration also aims to advance AI-driven tools like “co-scientists” that assist researchers in generating algorithms and code, significantly speeding up scientific workflows. Additional areas of potential cooperation include breakthroughs in quantum computing, materials science, synthetic biology, subsurface and geothermal energy resources, environmental remediation, and the development of open science-optimized AI models. This partnership builds on NVIDIA’s growing collaboration with the DOE, highlighted during the NVIDIA GTC Washington, D.C. conference. Notably, NVIDIA and Oracle are jointly building the Department’s largest supercomputer at Argonne National Laboratory. NVIDIA will also support the deployment of seven new high-performance computing systems across Argonne and Los Alamos National Laboratories, further advancing the DOE’s mission in technological leadership. As the pioneer of accelerated computing, NVIDIA has enabled the rapid training of large AI models and the simulation of complex physical systems at unprecedented scale and speed. With the Genesis Mission, the company is helping to fuel a new industrial revolution in the United States—one driven by AI, innovation, and national strategic advantage.