The Fifth National University Chemical Experiment Technology Exchange Conference was recently held at Wuhan University. Organized by the Teaching Steering Committee of Chemistry Specialty at Ministry of Education and the Teaching Steering Committee of University Chemistry Courses, the conference was hosted by the College of Chemistry and Molecular Sciences and the National Experimental Teaching Demonstration Center for Chemistry at Wuhan University. Over 150 experts and scholars from nearly 40 universities, including Peking University, Tsinghua University, Zhejiang University, Nanjing University, and the University of Science and Technology of China, gathered to discuss the latest advancements and best practices in chemical experiment teaching and laboratory management. During the conference's plenary session, several experts presented on cutting-edge topics and shared their research findings and personal experiences. Professor Zhang Jianrong from Nanjing University emphasized the importance of standardizing basic experimental operations. Professor Lin Xufeng from Zhejiang University discussed the development and practical implementation of new textbooks for general chemistry experiments. Professor Zhao Faqiong from Wuhan University explored the construction and improvement of comprehensive chemistry experiment courses. Professor Xu Xinhu from Tongji University highlighted innovative approaches in physical chemistry experiments, offering fresh insights into educational reform. Additionally, experimental technician Liu Haiyan from Wuhan University presented on the center’s extensive work in popular science and practical applications. A significant focus of the conference was on the integration of intelligent technologies into chemical experiment teaching and digital educational tools. Advanced engineer Li Tian from Peking University delivered a report titled "AI Empowering Smart Learning and Teaching: Explorations and Practices in Digital Transformation of Experimental Education," which highlighted the broad applications of artificial intelligence in laboratory settings. Senior experimental instructor Zheng Yuan from the University of Science and Technology of China also presented on "AI Empowers Innovative Teaching in Basic Chemistry Experiments," further engaging participants in discussions about the future of technology-enhanced education. The conference featured four specialized sessions, each dedicated to different areas of chemistry experiments: inorganic and analytical chemistry, organic chemistry and integrated innovation experiments (including chemical biology experiments), physical chemistry and computational chemistry experiments, and instrumental analysis and chemical engineering experiments. These sessions provided a platform for in-depth discussions on experimental teaching reforms, laboratory management, and the adoption of intelligent tools. Experts shared their practical experiences and case studies, enriching the academic discourse with real-world examples. To enhance the learning experience, attendees visited the National Experimental Teaching Demonstration Center for Chemistry at Wuhan University. They got firsthand insights into the center’s course structure, experimental scheduling, and instrument management practices. This visit allowed them to see how theoretical concepts are applied in a modern, well-equipped laboratory setting. Furthermore, the conference included the second meeting of the Teaching Guidance Committee of the National Experimental Teaching Demonstration Center for Chemistry at Wuhan University for 2025. This segment aimed to discuss and advance the strategic goals and initiatives of the center. Overall, the event fostered collaboration and knowledge sharing among leading chemists and educators, driving forward the field of chemical experiment teaching and laboratory management through the lens of technological innovation and best practices.