Text Based De Novo Molecule Generation On
Metrics
BLEU
Exact Match
Frechet ChemNet Distance (FCD)
Levenshtein
MACCS FTS
Morgan FTS
Parameter Count
RDK FTS
Text2Mol
Validity
Results
Performance results of various models on this benchmark
Comparison Table
| Model Name | BLEU | Exact Match | Frechet ChemNet Distance (FCD) | Levenshtein | MACCS FTS | Morgan FTS | Parameter Count | RDK FTS | Text2Mol | Validity |
|---|---|---|---|---|---|---|---|---|---|---|
| translation-between-molecules-and-natural | 85.4 | 30.2 | 1.20 | 16.07 | 83.4 | 68.4 | 770000000 | 74.6 | 55.4 | 90.5 |
| git-mol-a-multi-modal-large-language-model | 75.6 | 5.1 | - | 26.315 | 73.8 | 51.9 | - | 58.2 | - | 92.8 |
| unifying-molecular-and-textual | 75 | 21.2 | 0.061 | 27.39 | 87.4 | 69.7 | 220000000 | 76.7 | - | 79.2 |
| empowering-molecule-discovery-for-molecule | 85.7 | 28.0 | 0.41 | 17.14 | 90.3 | 73.9 | None | 80.5 | 59.3 | 89.9 |
| biot5-towards-generalized-biological | 87.2 | 52.2 | 0.353 | 12.776 | 90.7 | 77.9 | 252000000 | 83.5 | 57.9 | 100 |
| ldmol-text-conditioned-molecule-diffusion | 92.6 | 53.3 | 0.20 | 6.750 | 97.3 | 93.1 | - | 95.0 | - | 94.1 |
| translation-between-molecules-and-natural | 75.5 | 7.9 | 2.49 | 25.988 | 70.3 | 51.7 | 60000000 | 56.8 | 48.2 | 72.1 |
| molreflect-towards-fine-grained-in-context | 90.3 | 51.0 | - | 11.84 | 92.9 | 81.3 | - | 86.0 | - | 97.7 |
| biot5-enriching-cross-modal-integration-in | 86.7 | 41.3 | .43 | 15.097 | 88.6 | 73.4 | 252000000 | 80.1 | 57.6 | 100 |
| unifying-molecular-and-textual | 73.9 | 15.7 | 0.066 | 28.54 | 85.9 | 66 | 60000000 | 73.6 | - | 77.6 |
| molfm-a-multimodal-molecular-foundation-model | 80.3 | 16.9 | - | 20.868 | 83.4 | 72.1 | 13620000 | 66.2 | 57.3 | 85.9 |
| empowering-molecule-discovery-for-molecule | 79.0 | 13.9 | 0.57 | 24.91 | 84.7 | 62.4 | - | 70.8 | 57.1 | 88.7 |
| unifying-molecular-and-textual | 81.5 | 19.1 | 0.06 | 21.78 | 86.4 | 67.2 | 60000000 | 74.4 | - | 95.1 |
| text-guided-molecule-generation-with | 82.6 | 24.2 | 0.77 | 17.003 | 85.4 | 68.8 | 180000000 | 73.9 | 58.1 | 87.1 |
| molxpt-wrapping-molecules-with-text-for | - | 21.5 | 0.45 | - | 85.9 | 66.7 | 350000000 | 75.7 | 57.8 | 98.3 |
| translation-between-molecules-and-natural | 81.0 | 31.4 | 0.44 | 16.758 | 87.2 | 72.2 | 770000000 | 78.6 | 59.0 | 99.6 |
| translation-between-molecules-and-natural | 76.9 | 8.1 | 2.18 | 24.458 | 72.1 | 52.9 | 220000000 | 58.8 | 49.6 | 77.2 |
| molfm-a-multimodal-molecular-foundation-model | 82.2 | 21.0 | - | 19.445 | 85.4 | 75.8 | 296200000 | 69.7 | 58.3 | 89.2 |
| unifying-molecular-and-textual | 85.3 | 32.2 | .05 | 16.87 | 90.1 | 75.7 | 220000000 | 81.6 | - | 94.3 |
| text-guided-molecule-generation-with | 82.8 | 24.2 | 0.89 | 16.897 | 87.4 | 72.2 | 180000000 | 77.1 | 58.9 | 78.9 |