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Top investors share how they use AI

Venture capitalists have increasingly integrated artificial intelligence into their daily operations to identify promising startups and streamline internal workflows. Following a trend where investors use AI to scout for the next major breakthrough company, top funds from recent lists such as Seed 100 and Seed 40 now rely on chatbots and agents for market mapping, idea stress-testing, and creating searchable knowledge bases from call transcripts. Salil Deshpande of Uncorrelated Ventures described his use of an AI agent as a second brain that manages his back office, handles scheduling, and categorizes communications. He also utilizes a personalized system to answer portfolio questions by analyzing documents and providing citations. Similarly, Ann Miura Ko of Floodgate uses AI to ingest field notes from visits to over a dozen AI-native companies, allowing her to identify converging patterns that inform her investment thesis. In the realm of deal sourcing, investors are leveraging AI to find hidden gems. Anne Dwane of Village Global employs agentic workflows to maintain fresh networks of top-tier angel investors in emerging talent pools. Alex Bard at Redpoint Ventures uses internal AI systems to detect early momentum signals in startups, such as hiring velocity and product launches, while Sarah Smith of the Sarah Smith Fund utilizes a custom 100-point scoring framework to objectively evaluate inbound opportunities based on founder intensity and market fit. Operational efficiency has also been transformed. Lan Xuezhao of Basis Set notes that her engineering team has been building with AI weekly since 2017. Janet Bannister of Staircase Ventures automates daily briefings that include meeting objectives and background context, while Jeff Fluhr of Craft Ventures uses coding tools to rapidly prototype startup ideas, allowing him to test concepts with working products rather than abstract debates. Shan-Lyn Ma of Zola tracks news across her 50 portfolio companies using a custom AI assistant. Preparation for pitches has become more data-driven. Henry McNamara of Great Oaks Venture Capital uses natural language queries and tools like Claude to steelman his reasoning and test biases before internal debates. Sara Deshpande of Maven Ventures relies on Perplexity for market research and competitive analysis, while Jon Soberg of MS&AD Ventures uses AI to quickly scan the competitive landscape for target companies. Despite these technological advancements, many investors emphasize that AI has highlighted the value of human connection. Julie Lein of Urban Innovation Fund stated that AI has made her team lean more aggressively toward in-person events and coffee chats. She argues that in an AI-native world, real human-to-human interaction is the only differentiator that truly stands out. This shift suggests that while AI enhances speed and data analysis, the core of venture capital remains rooted in personal relationships and intuition.

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